Brinley has been on the ventilator since last Thursday, her infection isn't any better and her cultures continue to be positive. Dr.Wagle removed her central line today, he didn't want to remove it unless he absolutely had to because that is the line that she receives her TPN (nutrition, vitamins, etc) and her Lipids (fats) through, but since the culture has been positive for 5 days now he had no choice but to remove it. He's been wanting to do a Spinal tap since Friday morning but her platelets have been so low that he hasn't been able to do it, she's received 2 blood transfusions and they've had to give her platelets 4 times since Friday morning. Yesterday morning he consulted a Infectious disease specialist and he suggested to hold off on the spinal tap until the infection was under control and Brinley was less critical, he said the type of infection she has was rare to turn into Meningitis and he didn't feel it was worth the risk. They also repeated her Echo and her PDA (heart murmur) is still moderate in size, and isn't any larger then it was before the incident on Thursday night and in fact it was 1.6 in size on the previous Echo and was only 1.1 this time. Friday and Saturday she was so exhausted from being sick that she didn't move alot but Saturday night she started getting real restless and fighting the tube in her throat, they've been sedating her since then but I can't tell that it makes much of a difference she really wants to be off the ventilator and get that tube out of her throat and I really want her off of it too.. I haven't been able to hold her since last Tuesday, and I miss being able to kiss her little head and do Kangaroo care with her. Dr.Wagle said now that the central line is removed we should start seeing improvement within 48 hours. I really appreciate all the prayers you've been saying for Brinley, please continue to pray for her and be specific and ask God to treat the infection in her body and make her lungs strong so she can get off the ventilator.